CH CRL (R4)
0.9.0 - Draft

This page is part of the CH CRL (R4) (v0.9.0: STU Draft) based on FHIR R4. . For a full list of available versions, see the Directory of published versions

Artifacts Summary

This page provides a list of the FHIR artifacts defined as part of this implementation guide.

Structures: Logical Models

These define data models that represent the domain covered by this implementation guide in more business-friendly terms than the underlying FHIR resources.

CH CRL Cancer Report Logical Model

Logical model of the cancer report

Structures: Resource Profiles

These define constraints on FHIR resources for systems conforming to this implementation guide

CH CRL Bundle

Definition of the Bundle for reporting to the cancer registry

CH CRL Communication

Definition of the Communication for the date of informing the patient about the cancer registration

CH CRL Composition

Definition of the Composition for reporting to the cancer registry

CH CRL Condition Disease

Definition of the Condition for diseases

CH CRL Condition Final Cause of Death

Definition of the Condition for the final cause of death

CH CRL DocumentReference

Definition of the DocumentReference for the report as PDF

CH CRL Encounter Treatment Decision

Definition of the Encounter for the treatment decision

CH CRL Observation α-fetoprotein

Definition of the Observation for the α-fetoprotein

CH CRL Observation Ann Arbor Staging

Definition of the Observation for the Ann Arbor staging

CH CRL Observation Associated In-situ Tumour

Definition of the Observation for the associated in-situ tumour

CH CRL Observation Binet Staging

Definition of the Observation for the Binet staging

CH CRL Observation Breslow Thickness

Definition of the Observation for the Breslow thickness

CH CRL Observation cM

Definition of the Observation for the TNM clinical distant metastases category

CH CRL Observation cN

Definition of the Observation for the TNM clinical regional nodes category

CH CRL Observation COG ALL Staging

Definition of the Observation for the COG ALL staging

CH CRL Observation COG Staging

Definition of the Observation for the COG staging

CH CRL Observation cT

Definition of the Observation for the TNM clinical primary tumor category

CH CRL Observation Cerebrovascular Accident or Transient Ischemic Attack

Definition of the Observation for the cerebrovascular accident or transient ischemic attack

CH CRL Observation Charlson Index

Definition of the Observation for the Charlson index

CH CRL Observation Chronic Pulmonary Disease

Definition of the Observation for the chronic pulmonary disease

CH CRL Observation Circumferential Resection Margins

Definition of the Observation for the circumferential resection margins

CH CRL Observation Clinical Tumour Size

Definition of the Observation for the clinical tumour size

CH CRL Observation Congestive Heart Failure

Definition of the Observation for the congestive heart failure

CH CRL Observation Connective Tissue Disease - Rheumatic Disease

Definition of the Observation for the connective tissue disease - rheumatic disease

CH CRL Observation Creasman Grading System

Definition of the Observation for the Creasman grading system

CH CRL Observation DSSplus

Definition of the Observation for the DSSplus

CH CRL Observation Date of Incidence

Definition of the Observation for the date of incidence

CH CRL Observation Dementia

Definition of the Observation for the dementia

CH CRL Observation Diabetes Mellitus

Definition of the Observation for the diabetes mellitus

CH CRL Observation EBV

Definition of the Observation for the EBV

CH CRL Observation Elston/Ellis Grading System

Definition of the Observation for the Elston/Ellis grading system

CH CRL Observation FIGO Staging

Definition of the Observation for the FIGO staging

CH CRL Observation Gleason Biopsy Second Most Common or Highest Grade

Definition of the Observation for the Gleason biopsy second most common or highest grade

CH CRL Observation Gleason Biopsy Most Common Grade

Definition of the Observation for the Gleason biopsy most common grade

CH CRL Observation Gleason Excision Second Most Common or Highest Grade

Definition of the Observation for the Gleason excision second most common or highest grade

CH CRL Observation Gleason Excision Most Common Grade

Definition of the Observation for the Gleason excision most common grade

CH CRL Observation Gleason Score

Definition of the Observation for the Gleason score

CH CRL Observation β-hCG

Definition of the Observation for the β-hCG

CH CRL Observation HIV/AIDS

Definition of the Observation for HIV/AIDS

CH CRL Observation HPV/p16

Definition of the Observation for the HPV/p16

CH CRL Observation Hemiplegia / Paraplegia

Definition of the Observation for the hemiplegia / paraplegia

CH CRL Observation Her2 Receptor Status

Definition of the Observation for the Her2 receptor status

CH CRL Observation ICCC-3 Code

Definition of the Observation for the ICCC-3 code

CH CRL Observation ICCC-3 Extended Code

Definition of the Observation for the ICCC-3 extended code

CH CRL Observation ICCC-3 Main Group

Definition of the Observation for the ICCC-3 main group

CH CRL Observation ICD-10

Definition of the Observation for the ICD-10 code

CH CRL Observation ICD-O-3 Behaviour

Definition of the Observation for the ICD-O-3 behaviour code

CH CRL Observation ICD-O-3 Histological Grade

Definition of the Observation for the ICD-O-3 histological grade code

CH CRL Observation ICD-O-3 Laterality

Definition of the Observation for the ICD-O-3 laterality code

CH CRL Observation ICD-O-3 Morphology

Definition of the Observation for the ICD-O-3 morphology code

CH CRL Observation ICD-O-3 Morphology Post-transformation

Definition of the Observation for the ICD-O-3 morphology term after transformation

CH CRL Observation ICD-O-3 Morphology Pre-transformation

Definition of the Observation for the ICD-O-3 morphology term before change of main diagnosis

CH CRL Observation ICD-O-3 Topography

Definition of the Observation for the ICD-O-3 topography code

CH CRL Observation INRGSS Staging

Definition of the Observation for the INRGSS staging

CH CRL Observation IRSS Staging

Definition of the Observation for the IRSS staging

CH CRL Observation ISS Staging

Definition of the Observation for the ISS staging

CH CRL Observation LDH

Definition of the Observation for the LDH

CH CRL Observation Liver Disease

Definition of the Observation for the liver disease

CH CRL Observation Lugano Staging

Definition of the Observation for the Lugano staging

CH CRL Observation Lymphatic Invasion

Definition of the Observation for the lymphatic invasion

CH CRL Observation Metastases at Diagnosis Indicator

Definition of the Observation for the metastases at diagnosis indicator

CH CRL Observation Microsatellite Instability

Definition of the Observation for the microsatellite instability

CH CRL Observation Moderate to Severe Chronic Kidney Disease

Definition of the Observation for the moderate to severe chronic kidney disease

CH CRL Observation Myocardial Infarction

Definition of the Observation for the myocardial infarction

CH CRL Observation Number of Examined Regional Lymph Nodes

Definition of the Observation for the number of examined regional lymph nodes

CH CRL Observation Number of Examined Sentinel Lymph Nodes

Definition of the Observation for the number of examined sentinel lymph nodes

CH CRL Observation Number of Involved Regional Lymph Nodes

Definition of the Observation for the number of involved regional lymph nodes

CH CRL Observation Number of Positive Sentinel Lymph Nodes

Definition of the Observation for the number of positive sentinel lymph nodes

CH CRL Observation Oestrogen Receptor Status

Definition of the Observation for the oestrogen receptor status

CH CRL Observation pM

Definition of the Observation for the TNM pathologic distant metastases category

CH CRL Observation pN

Definition of the Observation for the TNM pathologic regional nodes category

CH CRL Observation PRETEXT Staging

Definition of the Observation for the PRETEXT staging

CH CRL Observation pT

Definition of the Observation for the TNM pathologic primary tumor category

CH CRL Observation Pathological Tumour Size

Definition of the Observation for the pathological tumour size

CH CRL Observation Peptic Ulcer Disease

Definition of the Observation for the peptic ulcer disease

CH CRL Observation Perineural Invasion

Definition of the Observation for the perineural invasion

CH CRL Observation Peripheral Vascular Disease

Definition of the Observation for the peripheral vascular disease

CH CRL Observation Pretreatment Prostate Specific Antigen

Definition of the Observation for the pretreatment prostate specific antigen (PSA)

CH CRL Observation Progesterone Receptor Status

Definition of the Observation for the progesterone receptor status

CH CRL Observation Rai Staging

Definition of the Observation for the Rai staging

CH CRL Observation Resection Margin In-situ Tumour

Definition of the Observation for the resection margin in-situ tumour

CH CRL Observation Resection Margin Invasive Tumour

Definition of the Observation for the resection margin invasive tumour

CH CRL Observation Residual In-situ Tumour

Definition of the Observation for the residual in-situ tumour

CH CRL Observation Residual Invasive Tumour

Definition of the Observation for the residual invasive tumour

CH CRL Observation Rhabdomyosarcoma Site Staging

Definition of the Observation for the Rhabdomyosarcoma site staging

CH CRL Observation SIOP Staging

Definition of the Observation for the SIOP staging

CH CRL Observation SalzerKuntschik Grading System

Definition of the Observation for the SalzerKuntschik grading system

CH CRL Observation Sentinel Lymph Node Assessment

Definition of the Observation for the sentinel lymph node assessment

CH CRL Observation Serum Tumour Markers

Definition of the Observation for the serum tumour markers

CH CRL Observation Shimada Grading System

Definition of the Observation for the Shimada grading system

CH CRL Observation St. Jude / Murphy Staging

Definition of the Observation for the St. Jude / Murphy staging

CH CRL Observation TNM Stage Group

Definition of the Observation for the TNM stage group

CH CRL Observation Topography of Metastases at Diagnosis

Definition of the Observation for the topography of metastases at diagnosis

CH CRL Observation Topography of Post-diagnosis Metastases

Definition of the Observation for the topography of post-diagnosis metastases

CH CRL Observation Toronto Tier II (Manual) Staging

Definition of the Observation for the Toronto Tier II (manual) staging

CH CRL Observation Tumour Proliferation Labeling

Definition of the Observation for the tumour proliferation labeling

CH CRL Observation Type of Recurrence/Transformation

Definition of the Observation for the type of recurrence/transformation

CH CRL Observation Venous Invasion

Definition of the Observation for the venous invasion

CH CRL Observation WHO(CNS) Grading System

Definition of the Observation for the WHO(CNS) grading system

CH CRL Observation WHO Grade Group

Definition of the Observation for the WHO grade group

CH CRL Observation a-Prefix of pTNM

Definition of the Observation for the a-Prefix of pTNM

CH CRL Observation m-Suffix of pT

Definition of the Observation for the m-Suffix of pT

CH CRL Observation y-Prefix of cTNM

Definition of the Observation for the y-Prefix of cTNM

CH CRL Observation y-Prefix of pTNM

Definition of the Observation for the y-Prefix of pTNM

CH CRL Organization

Definition of the Organization of which the organization department forms a part

CH CRL Organization Department

Definition of the Organization department (hospital) for reporting to the cancer registry

CH CRL Patient

Definition of the Patient for reporting to the cancer registry

CH CRL Practitioner

Definition of the Practitioner (resident physician) for reporting to the cancer registry

CH CRL Procedure Diagnostic Method

Definition of the Procedure for the diagnostic method(s)

CH CRL Procedure Method of First Detection

Definition of the Procedure for the method of first detection

CH CRL Procedure Treatment

Definition of the Procedure for the treatment

Structures: Extension Definitions

These define constraints on FHIR data types for systems conforming to this implementation guide

CH CRL Function of Contact Person Extension

Extension to define the function of contact person of an organization

CH CRL Procedure Treatment Goal

Extension to define the goal for the treatment as part of the first treatment complex

Terminology: Value Sets

These define sets of codes used by systems conforming to this implementation guide

NKRS - α-fetoprotein

The data item records the serum level of the tumour marker α-fetoprotein (AFP).

NKRS - Ann Arbor Staging

This data item is a last modification of the Ann Arbor classification for lymphoma.

NKRS - Basis of First Treatment Complex Decision

This data item records the basis of treatment decision for the entire first treatment complex. The first treatment complex includes all therapy steps planned after the diagnosis.

NKRS - Binet Staging

This data item records the stage of Chronic Lymphocytic Leukaemia (CLL) based on the cell count in the blood and bone marrow (lymphocytes, platelets), haemoglobin/ haematocrit, lymph nodes involvement, hepato- and/or splenomegaly.

NKRS - COG ALL Staging

COG ALL staging (for childhood B- precursor acute lymphoblastic leukemia, B-ALL) allows a uniform assessment of the extent of CNS involvement based on presence of blasts in the diagnostic cerebrospinal fluid (CSF).

NKRS - COG Staging

This data item records staging of Wilms’ tumour for pediatric patients acc. to pre-chemotherapy staging system developed by the National Wilms’ Tumor Study Group (NWTSG). Based exclusively on the anatomic extent of the tumour, without consideration of genetic, biologic, or molecular markers.

NKRS - Circumferential Resection Margins

The circumferential resection margin (CRM) is a surgically created plane produced during the removal of the rectum from its surroundings.

NKRS - Creasman Grading System

This data item records histopathological grade for uterine or endometrial cancer.

NKRS - DSSplus

The DSSplus (Durie-Salmon Plus staging system) is the revised Durie-Salmon staging system for multiple myeloma classification, based on MRI findings, FDG PET/CT findings, or both.

NKRS - Diabetes Mellitus

The data item records the presence and severity of diabetes mellitus at the time of diagnosis as pre-existing medical condition. Scores weight the estimated effect on patient survival.

NKRS - Diagnostic Methods Used

The data item records all diagnostic methods used.

NKRS - Elston/Ellis Grading System

This data item records the histopathological grade for breast cancer. It is also called the Nottingham Histological Score. The grade for an individual tumour is derived from an assessment of three morphological features (Tubule formation, Nuclear pleomorphism, Mitotic count), each of which is scored 1-3.

NKRS - FIGO Staging

FIGO Staging of gynecologic tumours is based on clinical staging, careful clinical examination before therapy, and surgical exploration.

NKRS - β-hCG

The data item records the level of serum tumour marker human chorionic gonadotropin (β-hCG).

NKRS - Her2 Receptor Status

The data item records the Her2 (human epidermal growth factor receptor 2) expression status of the tumour.

NKRS - ICCC-3 Code

This data item records detailed division of the diagnostic group according to the third revision of the 1996 International Classification of Childhood Cancer (ICCC-3).

NKRS - ICCC-3 Extended Code

This data item records detailed division of the diagnostic group according to the third revision of the 1996 International Classification of Childhood Cancer (ICCC-3).

NKRS - ICCC-3 Main Group

This data item records the main diagnostic group according to the third revision (2005) of the 1996 International Classification of Childhood Cancer (ICCC-3).

NKRS - INRGSS Staging

This data item records the paediatric stage classification of the International Neuroblastoma Risk Group Staging System (INRGSS).

NKRS - IRSS Staging

The paediatric International Retinoblastoma Staging System is based on extent of disease and the presence of overt extra-ocular extension after enucleation.

NKRS - ISS Staging

The data item records the International Staging System (ISS) for multiple myeloma.

NKRS - ICD-O-3 Behaviour

This data item records the behaviour of the neoplasm at time of diagnosis according to ICD-O.

NKRS - ICD-O-3 Histological Grade

The data item describes the neoplasm’s resemblance to normal (parent) tissue according to ICD-O.

NKRS - ICD-O-3 Laterality

Laterality describes the side of a paired organ or side of the body on which the reportable cancer originated.

NKRS - LDH

The data item records the levels of serum tumour marker lactate dehydrogenase (LDH).

NKRS - Liver Disease

The data item records the presence and severity of liver disease at the time of diagnosis as pre-existing medical condition. Scores weight the estimated effect on patient survival.

NKRS - Lugano Staging

The data item is a modification of the Ann Arbor classification for lymphoma.

NKRS - Lymphatic Invasion

The data item indicates the presence or absence of tumour cells in lymphatic vessels within and at the margins of the primary tumour, as well as afferent and efferent lymphatics, as noted microscopically by the pathologist.

NKRS - Method of First Detection

The data item records the method or circumstance by which the case came to medical attention and the cancer was first diagnosed.

NKRS - PRETEXT Staging

The PRETEXT (PRE-Treatment EXTent of tumor) staging system is used for malignant primary liver tumours of childhood before any therapy. The PRETEXT hepatoblastoma staging is based on Couinaud’s system of segmentation of the liver.

NKRS - Perineural Invasion

Perineural invasion is the process of neoplastic invasion of nerves.

NKRS - Rai Staging

This classification for Chronic Lymphocytic Leukaemia (CLL) includes 4 stages based on blood and bone marrow cell count (lymphocytes, platelets), haemoglobin/haematocrit, LN envolvement, hepato- and/or splenomegaly. The staging allows classification of patients into three risk categories (low, intermediary, high risk with median survival >12y, >8y and >2y, respectively).

NKRS - Residual In-situ Tumour

This data items records the in-situ tumour status after treatment. The R classification can be used following surgical treatment alone, after radiotherapy alone, after chemotherapy alone or following multimodal therapy. The status after treatment takes distant metastases into account.

NKRS - Residual Invasive Tumour

This data items records the invasive tumour status after treatment. The R classification can be used following surgical treatment alone, after radiotherapy alone, after chemotherapy alone or following multimodal therapy. The status after treatment takes distant metastases into account.

NKRS - Rhabdomyosarcoma Site Staging

Rhabdomyosarcoma staging is based on the classic TNM staging taking into account favourable/non favourable tumour sites. It is used in paediatric oncology.

NKRS - SIOP Staging

This data item records staging of Wilms’ tumor for pediatric patients acc. to post-chemotherapy staging system developed by the International Society of Pediatric Oncology (SIOP). Based exclusively on the anatomic extent of the tumor, without consideration of genetic, biologic, or molecular markers.

NKRS - SalzerKuntschik Grading System

This data item records the histopathological grade for breast cancer. It is also called the Nottingham Histological Score. The grade for an individual tumour is derived from an assessment of three morphological features (Tubule formation, Nuclear pleomorphism, Mitotic count), each of which is scored 1-3.

NKRS - Sentinel Lymph Node Assessment

The data item indicates whether the sentinel lymph node is excised and the result of the examination. The sentinel lymph node is the first lymph node to receive lymphatic drainage from a primary tumour.

NKRS - Serum Tumour Markers

The data item records the TNM S-categories as combination of levels for AFP, hCG, and LDH.

NKRS - Shimada Grading System

This data item records the grade for neuroblastoma, a frequent childhood cancer. Based on a grade of neuroblastic differentiation and mitosis-karyorrhexis index [MKI]) along with patient age at the time of diagnosis.

NKRS - St. Jude / Murphy Staging

The data item records the International Staging System (ISS) for multiple myeloma.

NKRS - TNM Stage Group

The data item records the UICC TNM stage group.

NKRS - Topography of Metastases

The data item identifies the distant site(s) of metastatic involvement at time of diagnosis or after disease recurrence.

NKRS - Toronto Tier II (Manual) Staging

The Toronto Paediatric Cancer Stage Guidelines recommend the malignancy-specific staging system most suitable for use by population registries for 16 of the most common childhood malignancies. The Guidelines include a two-tiered approach that provides less detailed criteria for registries with limited resources and/or limited data access (Tier 1) based on collapsing of the more detailed criteria (Tier 2).

NKRS - Treatment Goal

The goal for each treatment as part of the first treatment complex.

NKRS - Type of Recurrence/Transformation

The data item records the type of first recurrence of the disease or the occurrence of a transformation.

NKRS - Venous Invasion

The data item indicates the presence or absence of tumour cells in the walls of venous blood vessels, as noted microscopically by the pathologist.

NKRS - WHO(CNS) Grading System

Primary brain tumours are grouped according to the WHO classification based on the cell of origin, and the histological aggressiveness.

NKRS - WHO Grade Group

A five-grade group system based on the grading categories from Gleason score 2 to 10.

NKRS - cM

The data item records the absence or presence of distant metastases based on clinical investigation, imaging, endoscopy, surgical exploration without biopsy.

NKRS - cN

The data item records regional lymph nodes involvement based on clinical investigation, imaging, endoscopy, biopsy or surgical exploration.

NKRS - cT

The data item records tumour size based on clinical investigation, imaging, endoscopy, biopsy or surgical exploration.

NKRS - m-Suffix of pT

The data item records the unspecified multiplicity of multiple primary tumours at a single site.

NKRS - pM

The data item records the absence or presence of distant metastasis, based on pathological evidence after completion of surgical therapy or microscopic examination of metastasis.

NKRS - pN

The data item records the absence or presence and extent of regional lymph node metastasis, based on pathological evidence after completion of surgical therapy.

NKRS - pT

This data item records the extent of the primary tumour based on pathological (histological) evidence after completion of surgical therapy.

Terminology: Code Systems

These define new code systems used by systems conforming to this implementation guide

NKRS - α-fetoprotein

The data item records the serum level of the tumour marker α-fetoprotein (AFP). α-fetoprotein (Variable number: 5.5.1) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - Ann Arbor Staging

This data item is a last modification of the Ann Arbor classification for lymphoma. Ann Arbor staging (Variable number: 4.18) in 'NATIONAL CANCER DATA DICTIONARY, V 1.2, Part A, BASIC VARIABLES for Adults, Adolescents, and Children'

NKRS - Basis of First Treatment Complex Decision

This data item records the basis of treatment decision for the entire first treatment complex. The first treatment complex includes all therapy steps planned after the diagnosis. Basis of first treatment complex decision (Variable number: 7.1) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - Binet Staging

This data item records the stage of Chronic Lymphocytic Leukaemia (CLL) based on the cell count in the blood and bone marrow (lymphocytes, platelets), haemoglobin/ haematocrit, lymph nodes involvement, hepato- and/or splenomegaly. Binet staging (Variable number: 4.27) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - COG ALL Staging

COG ALL staging (for childhood B- precursor acute lymphoblastic leukemia, B-ALL) allows a uniform assessment of the extent of CNS involvement based on presence of blasts in the diagnostic cerebrospinal fluid (CSF). COG ALL staging (Variable number: 4.20) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - COG Staging

This data item records staging of Wilms’ tumour for pediatric patients acc. to pre-chemotherapy staging system developed by the National Wilms’ Tumor Study Group (NWTSG). Based exclusively on the anatomic extent of the tumour, without consideration of genetic, biologic, or molecular markers. COG staging (Variable number: 4.19) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - Circumferential Resection Margins

The circumferential resection margin (CRM) is a surgically created plane produced during the removal of the rectum from its surroundings. Circumferential resection margins (Variable number: 5.4.1) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - Creasman Grading System

This data item records histopathological grade for uterine or endometrial cancer. Creasman grading system (Variable number: 4.34) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - DSSplus

The DSSplus (Durie-Salmon Plus staging system) is the revised Durie-Salmon staging system for multiple myeloma classification, based on MRI findings, FDG PET/CT findings, or both. DSSplus (Variable number: 4.30) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - Diabetes Mellitus

The data item records the presence and severity of diabetes mellitus at the time of diagnosis as pre-existing medical condition. Scores weight the estimated effect on patient survival. Diabetes mellitus (Variable number: 10.1) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part B1, SUPPLEMENTARY VARIABLES for Adults (15.10.2019)' (EN, DE, FR, IT)

NKRS - Diagnostic Methods Used

The data item records all diagnostic methods used. Diagnostic method(s) used (Variable number: 2.8) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - Elston/Ellis Grading System

This data item records the histopathological grade for breast cancer. It is also called the Nottingham Histological Score. The grade for an individual tumour is derived from an assessment of three morphological features (Tubule formation, Nuclear pleomorphism, Mitotic count), each of which is scored 1-3. Elston/Ellis grading system (Variable number: 4.35) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - FIGO Staging

FIGO Staging of gynecologic tumours is based on clinical staging, careful clinical examination before therapy, and surgical exploration. FIGO staging (Variable number: 4.21) in 'NATIONAL CANCER DATA DICTIONARY, V 1.2, Part A, BASIC VARIABLES for Adults, Adolescents, and Children'

NKRS - β-hCG

The data item records the level of serum tumour marker human chorionic gonadotropin (β-hCG). β-hCG (Variable number: 5.5.2) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - Her2 Receptor Status

The data item records the Her2 (human epidermal growth factor receptor 2) expression status of the tumour. Her2 receptor status (Variable number: 5.1.3) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - ICCC-3 Code

This data item records detailed division of the diagnostic group according to the third revision of the 1996 International Classification of Childhood Cancer (ICCC-3). ICCC-3 code (Variable number: 3.9.2) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - ICCC-3 Extended Code

This data item records detailed division of the diagnostic group according to the third revision of the 1996 International Classification of Childhood Cancer (ICCC-3). ICCC-3 code (Variable number: 3.9.3) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - ICCC-3 Main Group

This data item records the main diagnostic group according to the third revision (2005) of the 1996 International Classification of Childhood Cancer (ICCC-3). ICCC-3 main group (Variable number: 3.9.1) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - INRGSS Staging

This data item records the paediatric stage classification of the International Neuroblastoma Risk Group Staging System (INRGSS). INRGSS staging (Variable number: 4.22) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - IRSS Staging

The paediatric International Retinoblastoma Staging System is based on extent of disease and the presence of overt extra-ocular extension after enucleation. IRSS staging (Variable number: 4.23) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - ISS Staging

The data item records the International Staging System (ISS) for multiple myeloma. ISS staging (Variable number: 4.29) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - ICD-O-3 Behaviour

This data item records the behaviour of the neoplasm at time of diagnosis according to ICD-O. ICD-O Behaviour (Variable number: 3.6.1) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - ICD-O-3 Histological Grade

The data item describes the neoplasm’s resemblance to normal (parent) tissue according to ICD-O. ICD-O Histological Grade (Variable number: 3.7) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - ICD-O-3 Laterality

Laterality describes the side of a paired organ or side of the body on which the reportable cancer originated. Laterality (Variable number: 3.8) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - LDH

The data item records the levels of serum tumour marker lactate dehydrogenase (LDH). LDH (Variable number: 5.5.3) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - Liver Disease

The data item records the presence and severity of liver disease at the time of diagnosis as pre-existing medical condition. Scores weight the estimated effect on patient survival. Liver Disease (Variable number: 10.2) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part B1, SUPPLEMENTARY VARIABLES for Adults (15.10.2019)' (EN, DE, FR, IT)

NKRS - Lugano Staging

The data item is a modification of the Ann Arbor classification for lymphoma. Lugano staging (Variable number: 4.24) in 'NATIONAL CANCER DATA DICTIONARY, V 1.2, Part A, BASIC VARIABLES for Adults, Adolescents, and Children'

NKRS - Lymphatic Invasion

The data item indicates the presence or absence of tumour cells in lymphatic vessels within and at the margins of the primary tumour, as well as afferent and efferent lymphatics, as noted microscopically by the pathologist. Lymphatic invasion (Variable number: 4.14) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - Method of First Detection

The data item records the method or circumstance by which the case came to medical attention and the cancer was first diagnosed. Method of first detection (Variable number: 2.6) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - PRETEXT Staging

The PRETEXT (PRE-Treatment EXTent of tumor) staging system is used for malignant primary liver tumours of childhood before any therapy. The PRETEXT hepatoblastoma staging is based on Couinaud’s system of segmentation of the liver. PRETEXT staging (Variable number: 4.25) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - Perineural Invasion

Perineural invasion is the process of neoplastic invasion of nerves. Perineural invasion (Variable number: 4.16) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - Rai Staging

This classification for Chronic Lymphocytic Leukaemia (CLL) includes 4 stages based on blood and bone marrow cell count (lymphocytes, platelets), haemoglobin/haematocrit, LN envolvement, hepato- and/or splenomegaly. The staging allows classification of patients into three risk categories (low, intermediary, high risk with median survival >12y, >8y and >2y, respectively). Rai staging (Variable number: 4.26) in 'NATIONAL CANCER DATA DICTIONARY, V 1.2, Part A, BASIC VARIABLES for Adults, Adolescents, and Children'

NKRS - Residual In-situ Tumour

This data items records the in-situ tumour status after treatment. The R classification can be used following surgical treatment alone, after radiotherapy alone, after chemotherapy alone or following multimodal therapy. The status after treatment takes distant metastases into account. Residual in-situ tumour (Variable number: 6.2) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - Residual Invasive Tumour

This data items records the invasive tumour status after treatment. The R classification can be used following surgical treatment alone, after radiotherapy alone, after chemotherapy alone or following multimodal therapy. The status after treatment takes distant metastases into account. Residual invasive tumour (Variable number: 6.1) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - Rhabdomyosarcoma Site Staging

Rhabdomyosarcoma staging is based on the classic TNM staging taking into account favourable/non favourable tumour sites. It is used in paediatric oncology. Rhabdomyosarcoma site staging (Variable number: 4.28) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - SIOP Staging

This data item records staging of Wilms’ tumor for pediatric patients acc. to post-chemotherapy staging system developed by the International Society of Pediatric Oncology (SIOP). Based exclusively on the anatomic extent of the tumor, without consideration of genetic, biologic, or molecular markers. SIOP staging (Variable number: 4.31) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - SalzerKuntschik Grading System

This data item records the histopathological grade for breast cancer. It is also called the Nottingham Histological Score. The grade for an individual tumour is derived from an assessment of three morphological features (Tubule formation, Nuclear pleomorphism, Mitotic count), each of which is scored 1-3. SalzerKuntschik grading system (Variable number: 4.36) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - Sentinel Lymph Node Assessment

The data item indicates whether the sentinel lymph node is excised and the result of the examination. The sentinel lymph node is the first lymph node to receive lymphatic drainage from a primary tumour. Sentinel lymph node assessment (Variable number: 6.5) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - Serum Tumour Markers

The data item records the TNM S-categories as combination of levels for AFP, hCG, and LDH. Serum tumour markers (Variable number: 5.5.4) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - Shimada Grading System

This data item records the grade for neuroblastoma, a frequent childhood cancer. Based on a grade of neuroblastic differentiation and mitosis-karyorrhexis index [MKI]) along with patient age at the time of diagnosis. Shimada grading system (Variable number: 4.37) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - St. Jude / Murphy Staging

The data item records the International Staging System (ISS) for multiple myeloma. St. Jude / Murphy staging (Variable number: 4.32) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - TNM Stage Group

The data item records the UICC TNM stage group. TNM stage group (Variable number: 4.17) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - Topography of Metastases

The data item identifies the distant site(s) of metastatic involvement at time of diagnosis or after disease recurrence. Sentinel lymph node assessment (Variable number: 6.5) / Topography(s) of post-diagnosis metastases (Variable number: 8.6) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - Toronto Tier II (Manual) Staging

The Toronto Paediatric Cancer Stage Guidelines recommend the malignancy-specific staging system most suitable for use by population registries for 16 of the most common childhood malignancies. The Guidelines include a two-tiered approach that provides less detailed criteria for registries with limited resources and/or limited data access (Tier 1) based on collapsing of the more detailed criteria (Tier 2). Toronto Tier II (manual) staging (Variable number: 4.33.2) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - Type of Recurrence/Transformation

The data item records the type of first recurrence of the disease or the occurrence of a transformation. Type of recurrence(s)/transformation(s) (Variable number: 8.1) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS Variables

NKRS codes for data elements for which there is no international code (e.g. LOINC or SNOMED CT) that accurately describes the meaning of the NKRS variable. This code system is based on 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT) and 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part B1, SUPPLEMENTARY VARIABLES for Adults (15.10.2019)' (EN, DE, FR, IT).

NKRS - Venous Invasion

The data item indicates the presence or absence of tumour cells in the walls of venous blood vessels, as noted microscopically by the pathologist. Venous invasion (Variable number: 4.15) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - WHO Grade Group

A five-grade group system based on the grading categories from Gleason score 2 to 10. WHO grade group (Variable number: 5.2.7) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - cM

The data item records the absence or presence of distant metastases based on clinical investigation, imaging, endoscopy, surgical exploration without biopsy. cM (Variable number: 4.5) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - cN

The data item records regional lymph nodes involvement based on clinical investigation, imaging, endoscopy, biopsy or surgical exploration. cN (Variable number: 4.4) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - cT

The data item records tumour size based on clinical investigation, imaging, endoscopy, biopsy or surgical exploration. cT (Variable number: 4.3) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - m-Suffix of pT

The data item records the unspecified multiplicity of multiple primary tumours at a single site. m-Suffix of pT (Variable number: 4.9) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - pM

The data item records the absence or presence of distant metastasis, based on pathological evidence after completion of surgical therapy or microscopic examination of metastasis. pM (Variable number: 4.13) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - pN

The data item records the absence or presence and extent of regional lymph node metastasis, based on pathological evidence after completion of surgical therapy. pN (Variable number: 4.10) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

NKRS - pT

This data item records the extent of the primary tumour based on pathological (histological) evidence after completion of surgical therapy. pT (Variable number: 4.8) in 'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children (23.12.2019)' (EN, DE, FR, IT)

Example: Example Instances

These are example instances that show what data produced and consumed by systems conforming with this implementation guide might look like

Abteilung Gastroenterologie

Example for Organization

Abteilung Minimum

Example for Organization

Abteilung Onkologie

Example for Organization

Abteilung Pathologie

Example for Organization

Agnes Bauer

Example for Practitioner

α-fetoprotein - AFP1

Example for Observation for the α-fetoprotein

α-fetoprotein - Not Performed

Example for Observation for the α-fetoprotein

α-fetoprotein - Unknown

Example for Observation for the α-fetoprotein

Ann Arbor Staging - I

Example for Observation for the Ann Arbor staging

Ann Arbor Staging - I+A

Example for Observation for the Ann Arbor staging

Ann Arbor Staging - Local Code

Example for Observation for the Ann Arbor staging

Ann Arbor Staging - Unknown

Example for Observation for the Ann Arbor staging

Associated In-situ Tumour - No

Example for Observation for the associated in-situ tumour

Associated In-situ Tumour - Unknown

Example for Observation for the associated in-situ tumour

Associated In-situ Tumour - Yes

Example for Observation for the associated in-situ tumour

Binet Staging - B

Example for Observation for the Binet staging

Binet Staging - Unknown

Example for Observation for the Binet staging

Breslow Thickness - 2.0 mm

Example for Observation for the Breslow thickness

Breslow Thickness - Unknown

Example for Observation for the Breslow thickness

Bundle from Organization

Example for Bundle for reporting to the cancer registry

Bundle from Practitioner

Example for Bundle for reporting to the cancer registry

Bundle UC 1a Gastro (2018-12-01)

Example for Bundle for reporting to the cancer registry

Bundle UC 1a Gastro (2019-06-17)

Example for Bundle for reporting to the cancer registry

Bundle UC 1a Info (2018-12-07)

Example for Bundle for reporting to the cancer registry

Bundle UC 1a Ops (2018-12-14)

Example for Bundle for reporting to the cancer registry

Bundle UC 1a Patho (2018-12-02)

Example for Bundle for reporting to the cancer registry

Bundle UC 1a Patho (2018-12-15)

Example for Bundle for reporting to the cancer registry

Bundle UC 1b Gastro (2018-12-01)

Example for Bundle for reporting to the cancer registry

Bundle UC 1b Gastro (2019-06-17)

Example for Bundle for reporting to the cancer registry

Bundle UC 1b Info (2018-12-07)

Example for Bundle for reporting to the cancer registry

Bundle UC 1b Ops (2018-12-14)

Example for Bundle for reporting to the cancer registry

Bundle UC 1b Patho (2018-12-02)

Example for Bundle for reporting to the cancer registry

Bundle UC 1b Patho (2018-12-15)

Example for Bundle for reporting to the cancer registry

COG ALL Staging - CNS1

Example for Observation for the COG ALL staging

COG ALL Staging - Unknown

Example for Observation for the COG ALL staging

COG Staging - II

Example for Observation for the COG staging

COG Staging - Unknown

Example for Observation for the COG staging

Cerebrovascular Accident or Transient Ischemic Attack - No

Example for Observation for the cerebrovascular accident or transient ischemic attack

Cerebrovascular Accident or Transient Ischemic Attack - Yes

Example for Observation for the cerebrovascular accident or transient ischemic attack

Charlson Index - 8

Example for Observation for the Charlson index

Chronic Pulmonary Disease - No

Example for Observation for the chronic pulmonary disease

Chronic Pulmonary Disease - Yes

Example for Observation for the chronic pulmonary disease

Circumferential Resection Margins - 0mm

Example for Observation for the circumferential resection margins

Circumferential Resection Margins - Unknown

Example for Observation for the circumferential resection margins

Clinical Tumour Size - 11 mm

Example for Observation for the clinical tumour size

Clinical Tumour Size - Unknown

Example for Observation for the clinical tumour size

Communication Robert Meier

Example for Communication

Communication Franz Minimum

Example for Communication

Composition from Organization

Example for Composition

Composition from Practitioner

Example for Composition

Composition UC 1a Gastro (2018-12-01)

Example for Composition

Composition UC 1a Gastro (2019-06-17)

Example for Composition

Composition UC 1a Info (2018-12-07)

Example for Composition

Composition UC 1a Ops (2018-12-14)

Example for Composition

Composition UC 1a Patho (2018-12-02)

Example for Composition

Composition UC 1a Patho (2018-12-15)

Example for Composition

Composition UC 1b Gastro (2018-12-01)

Example for Composition

Composition UC 1b Gastro (2019-06-17)

Example for Composition

Composition UC 1b Info (2018-12-07)

Example for Composition

Composition UC 1b Ops (2018-12-14)

Example for Composition

Composition UC 1b Patho 2018-12-02

Example for Composition

Composition UC 1b Patho (2018-12-15)

Example for Composition

Concomitant Disease A

Example for Condition for the diseases

Concomitant Disease B

Example for Condition for the diseases

Congestive Heart Failure - No

Example for Observation for the congestive heart failure

Congestive Heart Failure - Yes

Example for Observation for the congestive heart failure

Connective Tissue Disease - Rheumatic Disease - No

Example for Observation for the connective tissue disease - rheumatic disease

Connective Tissue Disease - Rheumatic Disease - Yes

Example for Observation for the connective tissue disease - rheumatic disease

Creasman Grading System - 1

Example for Observation for the Creasman grading system

Creasman Grading System - Unknown

Example for Observation for the Creasman grading system

DSSplus - IB

Example for Observation for the DSSplus

DSSplus - Unknown

Example for Observation for the DSSplus

Date of Incidence - 2018-12-02

Example for Observation for the date of incidence

Date of Incidence - 2018-12-02

Example for Observation for the date of incidence

Date of Incidence - 2018-12-15

Example for Observation for the date of incidence

Dementia - No

Example for Observation for the dementia

Dementia - Yes

Example for Observation for the dementia

Diabetes Mellitus - End-organ damage

Example for Observation for the diabetes mellitus

Diabetes Mellitus - No

Example for Observation for the diabetes mellitus

Diabetes Mellitus - Uncomplicated

Example for Observation for the diabetes mellitus

Diagnostic Method - CT Scan of Tumour

Example for Procedure for the diagnostic method(s)

Diagnostic Method - Biopsy of Primary Tumour (2018-12-01)

Example for Procedure for the diagnostic method(s)

Diagnostic Method - Biopsy of Primary Tumour (2018-12-02)

Example for Procedure for the diagnostic method(s)

Diagnostic Method - Biopsy of Primary Tumour (2018-12-14)

Example for Procedure for the diagnostic method(s)

Diagnostic Method - Biopsy of Primary Tumour (2019-06-17)

Example for Procedure for the diagnostic method(s)

Diagnostic Method - Endoscopy (2018-12-01)

Example for Procedure for the diagnostic method(s)

Diagnostic Method - Endoscopy (2018-12-02)

Example for Procedure for the diagnostic method(s)

Diagnostic Method - Endoscopy (2019-06-17)

Example for Procedure for the diagnostic method(s)

Diagnostic Method - Surgical Tissue from Operation (2018-12-14)

Example for Procedure for the diagnostic method(s)

Diagnostic Method - Surgical Tissue from Operation (2018-12-15)

Example for Procedure for the diagnostic method(s)

Diagnostic Method - Unknown

Example for Procedure for the diagnostic method(s)

Report as PDF from Hospital Minimum

Example for DocumentReference for the report as PDF

Report as PDF from Practitioner Minimum

Example for DocumentReference for the report as PDF

Report as PDF UC 1a Gastro (2018-12-01)

Example for DocumentReference for the report as PDF

Report as PDF UC 1a Gastro (2019-06-17)

Example for DocumentReference for the report as PDF

Report as PDF UC 1a Info (2018-12-07)

Example for DocumentReference for the report as PDF

Report as PDF UC 1a Ops (2018-12-14)

Example for DocumentReference for the report as PDF

Report as PDF UC 1a Patho (2018-12-02)

Example for DocumentReference for the report as PDF

Report as PDF UC 1a Patho (2018-12-15)

Example for DocumentReference for the report as PDF

EBV - No

Example for Observation for the EBV

EBV - Unknown

Example for Observation for the EBV

EBV - Yes

Example for Observation for the EBV

Else Zimmerli

Example for Patient (deceased)

Elston/Ellis Grading System - 2

Example for Observation for the Elston/Ellis grading system

Elston/Ellis Grading System - Unknown

Example for Observation for the Elston/Ellis grading system

Emma Minimum

Example for Practitioner

FIGO Staging - I

Example for Observation for the FIGO staging

FIGO Staging - IIIA1i

Example for Observation for the FIGO staging

FIGO Staging - Unknown

Example for Observation for the FIGO staging

Final Cause of Death

Example for Condition for the final cause of death

Final Cause of Death - Local Code

Example for Condition for the final cause of death

Franz Minimum

Example for Patient

Gleason Biopsy Most Common Grade - 2

Example for Observation for the Gleason biopsy most common grade

Gleason Biopsy Second Most Common or Highest Grade - 3

Example for Observation for the Gleason biopsy second most common or highest grade

Gleason Excision Most Common Grade - 3

Example for Observation for the Gleason excision most common grade

Gleason Excision Second Most Common or Highest Grade - 3

Example for Observation for the Gleason excision second most common or highest grade

Gleason Score - 6

Example for Observation for the Gleason score

Gleason Score - Unknown

Example for Observation for the Gleason score

β-hCG - Not Performed

Example for Observation for the β-hCG

β-hCG - Unknown

Example for Observation for the β-hCG

β-hCG - hCG2

Example for Observation for the β-hCG

HIV/AIDS - No

Example for Observation for the HIV/AIDS

HIV/AIDS - Yes

Example for Observation for the HIV/AIDS

HPV/p16 - No

Example for Observation for the HPV/p16

HPV/p16 - Unknown

Example for Observation for the HPV/p16

HPV/p16 - Yes

Example for Observation for the HPV/p16

Hemiplegia / Paraplegia - No

Example for Observation for the hemiplegia / paraplegia

Hemiplegia / Paraplegia - Yes

Example for Observation for the hemiplegia / paraplegia

Her2 Receptor Status - Not Performed

Example for Observation for the Her2 receptor status

Her2 Receptor Status - Overexpressed

Example for Observation for the Her2 receptor status

Her2 Receptor Status - Unknown

Example for Observation for the Her2 receptor status

ICCC-3 Code - VIIIa

Example for Observation for the ICCC-3 code

ICCC-3 Extended Code - Ia.4

Example for Observation for the ICCC-3 extended code

ICCC-3 Extended Code - Not Applicable

Example for Observation for the ICCC-3 extended code

ICCC-3 Main Group - VIII

Example for Observation for the ICCC-3 main group

ICD-10 - C25

Example for Observation for the ICD-10 code

ICD-10 - Kolon (2018-12-02)

Example for Observation for the ICD-10 code

ICD-10 - Kolon (preliminary)

Example for Observation for the ICD-10 code

ICD-O-3 Behaviour - Malignant

Example for Observation for the ICD-O-3 behaviour code

ICD-O-3 Behaviour - Malignant (2018-12-02)

Example for Observation for the ICD-O-3 behaviour code

ICD-O-3 Behaviour - Malignant (2018-12-15)

Example for Observation for the ICD-O-3 behaviour code

ICD-O-3 Histological Grade - Grade III (2018-12-02)

Example for Observation for the ICD-O-3 histological grade code

ICD-O-3 Histological Grade - Grade III (2018-12-15)

Example for Observation for the ICD-O-3 histological grade code

ICD-O-3 Histological Grade - Unknown

Example for Observation for the ICD-O-3 histological grade code

ICD-O-3 Laterality - Unilateral, NOS

Example for Observation for the ICD-O-3 laterality code

ICD-O-3 Laterality - NA (2018-12-02)

Example for Observation for the ICD-O-3 laterality code

ICD-O-3 Laterality - NA (2018-12-15)

Example for Observation for the ICD-O-3 laterality code

ICD-O-3 Morphology - Adenokarzinom

Example for Observation for the ICD-O-3 morphology code

ICD-O-3-Morphology - Muzinöses Adenokarzinom (2018-12-02)

Example for Observation for the ICD-O-3 morphology code

ICD-O-3 Morphology - Muzinöses Adenokarzinom (2018-12-15)

Example for Observation for the ICD-O-3 morphology code

ICD-O-3 Topography - Pankreaskörper

Example for Observation for the ICD-O-3 topography code

ICD-O-3 Topography - Flexura hepatica (2018-12-02)

Example for Observation for the ICD-O-3 topography code

ICD-O-3 Topography - Flexura hepatica (2018-12-15)

Example for Observation for the ICD-O-3 topography code

ICD-O-3 Morphology Post-transformation - 9861/3

Example for Observation for the ICD-O-3 morphology term after transformation

ICD-O-3 Morphology Pre-transformation - 9950/3

Example for Observation for the ICD-O-3 morphology term before change of main diagnosis

INRGSS Staging - M

Example for Observation for the INRGSS staging

INRGSS Staging - Unknown

Example for Observation for the INRGSS staging

IRSS Staging - Unknown

Example for Observation for the IRSS staging

IRSS Staging - cIVa.1

Example for Observation for the IRSS staging

ISS Staging - II

Example for Observation for the ISS staging

ISS Staging - Unknown

Example for Observation for the ISS staging

LDH - LDH3

Example for Observation for the LDH

LDH - Not Performed

Example for Observation for the LDH

LDH - Unknown

Example for Observation for the LDH

Liver Disease - Mild

Example for Observation for the liver disease

Liver Disease - Moderate to Severe

Example for Observation for the liver disease

Liver Disease - No

Example for Observation for the liver disease

Lugano Staging - I

Example for Observation for the Lugano staging

Lugano Staging - Unknown

Example for Observation for the Lugano staging

Lymphatic invasion - L0

Example for Observation for the lymphatic invasion

Lymphatic invasion - L1 (2018-12-02)

Example for Observation for the lymphatic invasion

Lymphatic invasion - L1 (2018-12-15)

Example for Observation for the lymphatic invasion

Metastases at Diagnosis Indicator - No

Example for Observation for the metastases at diagnosis indicator

Metastases at Diagnosis Indicator - Unknown

Example for Observation for the metastases at diagnosis indicator

Metastases at Diagnosis Indicator - Yes

Example for Observation for the metastases at diagnosis indicator

Method of First Detection - Clinical Symptoms

Example for Procedure for the method of first detection

Method of First Detection - Unknown

Example for Procedure for the method of first detection

Microsatellite Instability - No

Example for Observation for the microsatellite instability

Microsatellite Instability - Unknown

Example for Observation for the microsatellite instability

Microsatellite Instability - Yes

Example for Observation for the microsatellite instability

Moderate to Severe Chronic Kidney Disease - No

Example for Observation for the moderate to severe chronic kidney disease

Moderate to Severe Chronic Kidney Disease - Yes

Example for Observation for the moderate to severe chronic kidney disease

Myocardial Infarction - No

Example for Observation for the myocardial infarction

Myocardial Infarction - Yes

Example for Observation for the myocardial infarction

Number of Examined Regional Lymph Nodes - 7

Example for Observation for the number of examined regional lymph nodes

Number of Examined Regional Lymph Nodes - 18 (2018-12-02)

Example for Observation for the number of examined regional lymph nodes

Number of Examined Regional Lymph Nodes - 18 (2018-12-15)

Example for Observation for the number of examined regional lymph nodes

Number of Examined Regional Lymph Nodes - Unknown

Example for Observation for the number of examined regional lymph nodes

Number of Examined Sentinel Lymph Nodes - 4

Example for Observation for the number of examined sentinel lymph nodes

Number of Examined Sentinel Lymph Nodes - Unknown

Example for Observation for the number of examined sentinel lymph nodes

Number of Involved Regional Lymph Nodes - 2

Example for Observation for the number of involved regional lymph nodes

Number of Involved Regional Lymph Nodes - 0 (2018-12-02)

Example for Observation for the number of involved regional lymph nodes

Number of Involved Regional Lymph Nodes - 0 (2018-12-15)

Example for Observation for the number of involved regional lymph nodes

Number of Involved Regional Lymph Nodes - Unknown

Example for Observation for the number of involved regional lymph nodes

Number of Positive Sentinel Lymph Nodes - 6

Example for Observation for the number of positive sentinel lymph nodes

Number of Positive Sentinel Lymph Nodes - Unknown

Example for Observation for the number of positive sentinel lymph nodes

Oestrogen Receptor Status - 5 %

Example for Observation for the oestrogen receptor status

Oestrogen Receptor Status - Not Performed

Example for Observation for the oestrogen receptor status

Oestrogen Receptor Status - Positive

Example for Observation for the oestrogen receptor status

Oestrogen Receptor Status - Unknown

Example for Observation for the oestrogen receptor status

PRETEXT Staging - II

Example for Observation for the PRETEXT staging

PRETEXT Staging - Unknown

Example for Observation for the PRETEXT staging

Pathological Tumour Size - 11 mm

Example for Observation for the pathological tumour size

Pathological Tumour Size - Unknown

Example for Observation for the pathological tumour size

Peptic Ulcer Disease - No

Example for Observation for the peptic ulcer disease

Peptic Ulcer Disease - Yes

Example for Observation for the peptic ulcer disease

Perineural invasion - Pn0

Example for Observation for the perineural invasion

Perineural invasion - Pn0 (2018-12-02)

Example for Observation for the perineural invasion

Perineural invasion - Pn0 (2018-12-15)

Example for Observation for the perineural invasion

Peripheral Vascular Disease - No

Example for Observation for the peripheral vascular disease

Peripheral Vascular Disease - Yes

Example for Observation for the peripheral vascular disease

Pretreatment Prostate Specific Antigen - 80 ng/ml

Example for Observation for the pretreatment prostate specific antigen (PSA)

Pretreatment Prostate Specific Antigen - Unknown

Example for Observation for the pretreatment prostate specific antigen (PSA)

Primary disease

Example for Condition for the diseases

Progesterone Receptor Status - 3 %

Example for Observation for the progesterone receptor status

Progesterone Receptor Status - Negative

Example for Observation for the progesterone receptor status

Progesterone Receptor Status - Not Performed

Example for Observation for the progesterone receptor status

Progesterone Receptor Status - Unknown

Example for Observation for the progesterone receptor status

Rai Staging - II

Example for Observation for the Rai staging

Rai Staging - Unknown

Example for Observation for the Rai staging

Resection Margin In-situ Tumour - 2.0 mm

Example for Observation for the resection margin in-situ tumour

Resection Margin In-situ Tumour - Not Applicable

Example for Observation for the resection margin in-situ tumour

Resection Margin In-situ Tumour - Unknown

Example for Observation for the resection margin in-situ tumour

Resection Margin Invasive Tumour - 0.3 mm

Example for Observation for the resection margin invasive tumour

Resection Margin Invasive Tumour - Not Applicable

Example for Observation for the resection margin invasive tumour

Resection Margin Invasive Tumour - Unknown

Example for Observation for the resection margin invasive tumour

Residual In-situ Tumour - R1

Example for Observation for the residual in-situ tumour

Residual In-situ Tumour - Unknown

Example for Observation for the residual in-situ tumour

Residual Invasive Tumour - R0

Example for Observation for the residual invasive tumour

Residual Invasive Tumour - Unknown

Example for Observation for the residual invasive tumour

Rhabdomyosarcoma Site Staging - I

Example for Observation for the Rhabdomyosarcoma site staging

Rhabdomyosarcoma Site Staging - Unknown

Example for Observation for the Rhabdomyosarcoma site staging

Robert Meier

Example for Patient

SIOP Staging - Unknown

Example for Observation for the SIOP staging

SIOP Staging - yIII

Example for Observation for the SIOP staging

SalzerKuntschik Grading System - 1

Example for Observation for the SalzerKuntschik grading system

SalzerKuntschik Grading System - Unknown

Example for Observation for the SalzerKuntschik grading system

Secondary Disease

Example for Condition for the diseases

Sentinel Lymph Node Assessment - N0

Example for Observation for the sentinel lymph node assessment

Sentinel Lymph Node Assessment - Unknown

Example for Observation for the sentinel lymph node assessment

Serum Tumour Markers - Not Performed

Example for Observation for the serum tumour markers

Serum Tumour Markers - S3

Example for Observation for the serum tumour markers

Serum Tumour Markers - Unknown

Example for Observation for the serum tumour markers

Shimada Grading System - 1

Example for Observation for the Shimada grading system

Shimada Grading System - Unknown

Example for Observation for the Shimada grading system

Spital Minimum

Example for Organization

Spital Seeblick Doktor Gastro

Example for Organization

Spital Seeblick Doktor Patho

Example for Organization

Spital Seeblick Hans Egli

Example for Organization

St. Jude / Murphy Staging - I

Example for Observation for the St. Jude / Murphy staging

St. Jude / Murphy Staging - Unknown

Example for Observation for the St. Jude / Murphy staging

TNM Stage Group - Stage IV

Example for Observation for the TNM stage group

TNM Stage Group - Stage I (2018-12-02)

Example for Observation for the TNM stage group

TNM Stage Group - Stage IIA (2018-12-15)

Example for Observation for the TNM stage group

Topography of Metastases at Diagnosis - LYM

Example for Observation for the topography of metastases at diagnosis

Topography of Metastases at Diagnosis - MAR

Example for Observation for the topography of metastases at diagnosis

Topography of Metastases at Diagnosis - OTH

Example for Observation for the topography of metastases at diagnosis

Topography of Metastases at Diagnosis - Unknown

Example for Observation for the topography of metastases at diagnosis

Topography of Post-diagnosis Metastases - HEP

Example for Observation for the topography of post-diagnosis metastases

Topography of Post-diagnosis Metastases - Unknown

Example for Observation for the topography of post-diagnosis metastasess

Toronto Tier II (Manual) Staging - II

Example for Observation for the Toronto Tier II (manual) staging

Toronto Tier II (Manual) Staging - Unknown

Example for Observation for the Toronto Tier II (manual) staging

Treatment - Intraoperative Application of Chemotherapeutic Substances

Example for Procedure for the treatment

Treatment Decision - Tumour Board 2018-12-15

Example for Encounter for the treatment decision

Tumour Proliferation Labeling - 3 %

Example for Observation for the tumour proliferation labeling

Tumour Proliferation Labeling - Unknown

Example for Observation for the tumour proliferation labeling

Type of Recurrence/Transformation - Metastasis

Example for Observation for the type of recurrence/transformation

Type of Recurrence/Transformation - Progression

Example for Observation for the type of recurrence/transformation

Type of Recurrence/Transformation - Relapse

Example for Observation for the type of recurrence/transformation

Type of Recurrence/Transformation - Relapse (2019-06-17)

Example for Observation for the type of recurrence/transformation

Type of Recurrence/Transformation - Transformation

Example for Observation for the type of recurrence/transformation

Type of Recurrence/Transformation - Unknown

Example for Observation for the type of recurrence/transformation

Venous Invasion - V1

Example for Observation for the venous invasion

Venous Invasion - V0 (2018-12-02)

Example for Observation for the venous invasion

Venous Invasion - V0 (2018-12-15)

Example for Observation for the venous invasion

WHO(CNS) Grading System - 3

Example for Observation for the WHO(CNS) grading system

WHO(CNS) Grading System - Unknown

Example for Observation for the WHO(CNS) grading system

WHO Grade Group - Grade Group 2

Example for Observation for the WHO grade group

WHO Grade Group - Unknown

Example for Observation for the WHO grade group

a-Prefix of pTNM - Yes

Example for Observation for the a-Prefix of pTNM

a-Prefix of pTNM - No (2018-12-02)

Example for Observation for the a-Prefix of pTNM

a-Prefix of pTNM - No (2018-12-15)

Example for Observation for the a-Prefix of pTNM

cM - cM0

Example for Observation for the TNM clinical distant metastases category

cM - NA (2018-12-02)

Example for Observation for the TNM clinical distant metastases category

cM - NA (2018-12-15)

Example for Observation for the TNM clinical distant metastases category

cN - cN2

Example for Observation for the TNM clinical regional nodes category

cN - NA (2018-12-02)

Example for Observation for the TNM clinical regional nodes category

cN - NA (2018-12-15)

Example for Observation for the TNM clinical regional nodes category

cT - cT1

Example for Observation for the TNM clinical primary tumor category

cT - NA (2018-12-02)

Example for Observation for the TNM clinical primary tumor category

cT - NA (2018-12-15)

Example for Observation for the TNM clinical primary tumor category

m-Suffix of pT - 4

Example for Observation for the m-Suffix of pT

m-Suffix of pT - Unknown (2018-12-02)

Example for Observation for the m-Suffix of pT

m-Suffix of pT - Unknown (2018-12-15)

Example for Observation for the m-Suffix of pT

m-Suffix of pT - Unknown

Example for Observation for the m-Suffix of pT

m-Suffix of pT - Unspecified Multiplicity

Example for Observation for the m-Suffix of pT

pM - Unknown (2018-12-02)

Example for Observation for the TNM pathologic distant metastases category

pM - Unknown (2018-12-15)

Example for Observation for the TNM pathologic distant metastases category

pM - Unknown

Example for Observation for the TNM pathologic distant metastases category

pN - pN1(sn)

Example for Observation for the TNM pathologic regional nodes category

pN - pN0 (2018-12-02)

Example for Observation for the TNM pathologic regional nodes category

pN - pN0 (2018-12-15)

Example for Observation for the TNM pathologic regional nodes category

pT - pT1b2

Example for Observation for the TNM pathologic primary tumor category

pT - pT1 (2018-12-02)

Example for Observation for the TNM pathologic primary tumor category

pT - pT3 (2018-12-15)

Example for Observation for the TNM pathologic primary tumor category

y-Prefix of cTNM - No

Example for Observation for the y-Prefix of cTNM

y-Prefix of cTNM - No (2018-12-02)

Example for Observation for the y-Prefix of cTNM

y-Prefix of cTNM - No (2018-12-15)

Example for Observation for the y-Prefix of cTNM

y-Prefix of pTNM - Yes

Example for Observation for the y-Prefix of pTNM

y-Prefix of pTNM - No (2018-12-02)

Example for Observation for the y-Prefix of pTNM

y-Prefix of pTNM - No (2018-12-15)

Example for Observation for the y-Prefix of pTNM