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{
  "resourceType" : "CodeSystem",
  "id" : "nkrs-icdo3histologicalgrade",
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><h2>NKRS - ICD-O-3 Histological Grade</h2><div><p>The data item describes the neoplasm’s resemblance to normal (parent) tissue according to ICD-O.           <strong>ICD-O Histological Grade (Variable number: 3.7)</strong> in          'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children' see           <a href=\"https://www.nkrs.ch\">Nationale Krebsregistrierungsstelle</a> &gt; Partner im Gesundheitswesen &gt;         <a href=\"https://www.nicer.org/assets/files/krebsregistrierung/datadictionary_e-g-f-i.zip\">Information, Grundlagen und Datenstruktur zum KRG</a>.</p>\n</div><p>This code system http://fhir.ch/ig/ch-crl/CodeSystem/nkrs-icdo3histologicalgrade defines the following codes:</p><table class=\"codes\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td></tr><tr><td style=\"white-space:nowrap\">1<a name=\"nkrs-icdo3histologicalgrade-1\"> </a></td><td>Grade I</td><td>Well differentiated; Differentiated, NOS; Low grade</td></tr><tr><td style=\"white-space:nowrap\">2<a name=\"nkrs-icdo3histologicalgrade-2\"> </a></td><td>Grade II</td><td>Moderately (well) differentiated; Intermediate differentiation.</td></tr><tr><td style=\"white-space:nowrap\">3<a name=\"nkrs-icdo3histologicalgrade-3\"> </a></td><td>Grade III</td><td>Poorly differentiated; Dedifferentiated; High grade.</td></tr><tr><td style=\"white-space:nowrap\">4<a name=\"nkrs-icdo3histologicalgrade-4\"> </a></td><td>Grade IV</td><td>Undifferentiated; Anaplastic.</td></tr><tr><td style=\"white-space:nowrap\">5<a name=\"nkrs-icdo3histologicalgrade-5\"> </a></td><td>T-cell</td><td>T-cell; T-precursor.</td></tr><tr><td style=\"white-space:nowrap\">6<a name=\"nkrs-icdo3histologicalgrade-6\"> </a></td><td>B-cell</td><td>B-cell; Pre-B; B-precursor.</td></tr><tr><td style=\"white-space:nowrap\">7<a name=\"nkrs-icdo3histologicalgrade-7\"> </a></td><td>Null cell</td><td>Null cell; Non-T-non-B.</td></tr><tr><td style=\"white-space:nowrap\">8<a name=\"nkrs-icdo3histologicalgrade-8\"> </a></td><td>NK cell</td><td>NK cell; Natural killer cell.</td></tr></table></div>"
  },
  "url" : "http://fhir.ch/ig/ch-crl/CodeSystem/nkrs-icdo3histologicalgrade",
  "version" : "0.2.0",
  "name" : "NkrsIcdO3HistologicalGrade",
  "title" : "NKRS - ICD-O-3 Histological Grade",
  "status" : "draft",
  "date" : "2019-11-08T00:00:00+01:00",
  "publisher" : "NKRS - Nationale Krebsregistrierungsstelle",
  "contact" : [
    {
      "name" : "Foundation National Institute for Cancer Epidemiology and Registration (NICER)",
      "telecom" : [
        {
          "system" : "url",
          "value" : "https://www.nicer.org/"
        }
      ]
    }
  ],
  "description" : "The data item describes the neoplasm’s resemblance to normal (parent) tissue according to ICD-O.           **ICD-O Histological Grade (Variable number: 3.7)** in          \\'NATIONAL CANCER DATA DICTIONARY, V 1.1, Part A, BASIC VARIABLES for Adults, Adolescents, and Children\\' see           [Nationale Krebsregistrierungsstelle](https://www.nkrs.ch) > Partner im Gesundheitswesen >         [Information, Grundlagen und Datenstruktur zum KRG](https://www.nicer.org/assets/files/krebsregistrierung/datadictionary_e-g-f-i.zip).",
  "caseSensitive" : true,
  "valueSet" : "http://fhir.ch/ig/ch-crl/ValueSet/nkrs-icdo3histologicalgrade",
  "content" : "complete",
  "concept" : [
    {
      "code" : "1",
      "display" : "Grade I",
      "definition" : "Well differentiated; Differentiated, NOS; Low grade"
    },
    {
      "code" : "2",
      "display" : "Grade II",
      "definition" : "Moderately (well) differentiated; Intermediate differentiation."
    },
    {
      "code" : "3",
      "display" : "Grade III",
      "definition" : "Poorly differentiated; Dedifferentiated; High grade."
    },
    {
      "code" : "4",
      "display" : "Grade IV",
      "definition" : "Undifferentiated; Anaplastic."
    },
    {
      "code" : "5",
      "display" : "T-cell",
      "definition" : "T-cell; T-precursor."
    },
    {
      "code" : "6",
      "display" : "B-cell",
      "definition" : "B-cell; Pre-B; B-precursor."
    },
    {
      "code" : "7",
      "display" : "Null cell",
      "definition" : "Null cell; Non-T-non-B."
    },
    {
      "code" : "8",
      "display" : "NK cell",
      "definition" : "NK cell; Natural killer cell."
    }
  ]
}